BDBM50271240 CHEMBL3718522
SMILES [H][C@@]12CN(C[C@]1([H])[C@H]2c1cc(nn1CC(F)(F)F)-c1cnc(N)c(c1)C(F)(F)F)C1COC1
InChI Key InChIKey=LYOZBTIIBZSJSL-ATCWAGBWSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50271240
TargetMitogen-activated protein kinase kinase kinase 12(Homo sapiens (Human))
Wuxi Apptec
Curated by ChEMBL
Wuxi Apptec
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Binding affinity to N-terminally GST-tagged wild type human DLK (1 to 520 residues) expressed in sf21 insect cells using N-terminally His-tagged MKK4...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 12(Homo sapiens (Human))
Wuxi Apptec
Curated by ChEMBL
Wuxi Apptec
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of doxycycline inducible human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-bas...More data for this Ligand-Target Pair