BDBM50273511 1-[4-Difluoromethoxy-3-(tetrahydropyran-4-yloxy)phenyl]-butan-1-one::CHEMBL458297

SMILES CCCC(=O)c1ccc(OC(F)F)c(OC2CCOCC2)c1

InChI Key InChIKey=PHDDCAWVDPQOFB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50273511   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50273511(1-[4-Difluoromethoxy-3-(tetrahydropyran-4-yloxy)ph...)
Affinity DataIC50:  347nMAssay Description:Inhibition of full length human PDE4D2 expressed in Escherichia coli BL21 by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50273511(1-[4-Difluoromethoxy-3-(tetrahydropyran-4-yloxy)ph...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50273511(1-[4-Difluoromethoxy-3-(tetrahydropyran-4-yloxy)ph...)
Affinity DataIC50:  347nMAssay Description:Inhibition of full length human PDE4D2 expressed in Escherichia coli BL21 by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed