BDBM50274596 6-amino-9-benzyl-N-(2-methoxyethyl)-8-oxo-8,9-dihydro-7H-purine-2-carboxamide::CHEMBL484765::US11242345, Example P-2::US9708325, P-2
SMILES COCCNC(=O)c1nc(N)c2[nH]c(=O)n(Cc3ccccc3)c2n1
InChI Key InChIKey=JBMXBXFCHWLZSC-UHFFFAOYSA-N
Data 4 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50274596
Affinity DataEC50: 5nMAssay Description:Agonist activity at human TLR7 by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+6nMAssay Description:A stable HEK-Blue-hTLR8 cell line was purchased from InvivoGen (Cat. #: HEK-Blue-htlr8, San Diego, Calif., USA). These cells were designed for studyi...More data for this Ligand-Target Pair
Affinity DataEC50: 270nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
Affinity DataEC50: 270nMAssay Description:HEK-Blue-hTLR7 cells were incubated at a density of 250,000450,000 cells/mL in a volume of 180 μL in a 96-well plate in Dulbecco's Mod...More data for this Ligand-Target Pair