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BDBM50274853 (Z)-5-(3'-Hydroxybenzylidene)-2-thioxothiazolidin-4-one::CHEMBL457919

SMILES: Oc1cccc(C=C2SC(S)=NC2=O)c1

InChI Key: InChIKey=ZCQNEHSJTBPNPT-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50274853   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arylamine N-acetyltransferase 1


(Homo sapiens)
BDBM50274853
PNG
((Z)-5-(3'-Hydroxybenzylidene)-2-thioxothiazolidin-...)
Show SMILES Oc1cccc(C=C2SC(S)=NC2=O)c1
Show InChI InChI=1S/C10H7NO2S2/c12-7-3-1-2-6(4-7)5-8-9(13)11-10(14)15-8/h1-5,12H,(H,11,13,14)
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MMDB

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Similars

Article
PubMed
n/an/a 600n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of human recombinant NAT1 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's method


Bioorg Med Chem 17: 905-18 (2009)


Article DOI: 10.1016/j.bmc.2008.11.032
BindingDB Entry DOI: 10.7270/Q2PZ58Q3
More data for this
Ligand-Target Pair