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BDBM50274854 (Z)-5-(2'-Methoxybenzylidene)-2-thioxothiazolidin-4-one::CHEMBL512033

SMILES: COc1ccccc1C=C1SC(S)=NC1=O

InChI Key: InChIKey=WMOIFFNCPPXJMB-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50274854   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arylamine N-acetyltransferase 1


(Homo sapiens)
BDBM50274854
PNG
((Z)-5-(2'-Methoxybenzylidene)-2-thioxothiazolidin-...)
Show SMILES COc1ccccc1C=C1SC(S)=NC1=O
Show InChI InChI=1S/C11H9NO2S2/c1-14-8-5-3-2-4-7(8)6-9-10(13)12-11(15)16-9/h2-6H,1H3,(H,12,13,15)
PDB
MMDB

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Similars

Article
PubMed
n/an/a 1.76E+4n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of human recombinant NAT1 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's method


Bioorg Med Chem 17: 905-18 (2009)


Article DOI: 10.1016/j.bmc.2008.11.032
BindingDB Entry DOI: 10.7270/Q2PZ58Q3
More data for this
Ligand-Target Pair