BDBM50275157 CHEMBL453730::N-cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine

SMILES Cc1cc(C)n(n1)-c1nc(C)cc(NC2CCCCC2)n1

InChI Key InChIKey=USEMRPYUFJNFQN-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50275157   

TargetSmall conductance calcium-activated potassium channel protein 3(Rattus norvegicus)
Neurosearch

Curated by ChEMBL
LigandPNGBDBM50275157(CHEMBL453730 | N-cyclohexyl-2-(3,5-dimethyl-1H-pyr...)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [I125]apamine from Wistar rat recombinant SK3 channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 2(Rattus norvegicus (Rat))
Chapman University School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50275157(CHEMBL453730 | N-cyclohexyl-2-(3,5-dimethyl-1H-pyr...)
Affinity DataEC50:  7.48E+3nMAssay Description:Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed