BDBM50276169 (2R,4aR,10aR)-4a-Methyl-2-prop-1-ynyl-1,2,3,4,4a,9,10,10aoctahydrophenanthrene-2,7-diol::CHEMBL511982

SMILES CC#C[C@@]1(O)CC[C@]2(C)[C@H](CCc3cc(O)ccc23)C1

InChI Key InChIKey=UKQSPRJRVOKNNC-ZTFGCOKTSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50276169   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50276169((2R,4aR,10aR)-4a-Methyl-2-prop-1-ynyl-1,2,3,4,4a,9...)
Affinity DataIC50:  17nMAssay Description:Binding affinity to human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50276169((2R,4aR,10aR)-4a-Methyl-2-prop-1-ynyl-1,2,3,4,4a,9...)
Affinity DataIC50: >5.00E+3nMAssay Description:Transrepression activity at GR in human SW1353 cells assessed as inhibition of IL1-stimulated MMP13 production after 24 hrs by whole cell ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed