BDBM50277289 CHEMBL507114::N-(quinolin-8-yl)-6-(sulfamoylamino)hexanamide

SMILES NS(=O)(=O)NCCCCCC(=O)Nc1cccc2cccnc12

InChI Key InChIKey=IQEBALPYRTUOEG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277289   

TargetHistone deacetylase 6(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50277289(CHEMBL507114 | N-(quinolin-8-yl)-6-(sulfamoylamino...)
Affinity DataIC50:  390nMAssay Description:Inhibition of human recombinant N-terminal histidine-tagged HDAC6 expressed in baculovirus by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50277289(CHEMBL507114 | N-(quinolin-8-yl)-6-(sulfamoylamino...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged HDAC1 expressed in baculovirus by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed