BDBM50277320 4-(pyridin-4-ylmethylamino)-N-(4-(trifluoromethyl)phenyl)isothiazole-3-carboxamide::CHEMBL475704
SMILES FC(F)(F)c1ccc(NC(=O)c2nscc2NCc2ccncc2)cc1
InChI Key InChIKey=DNCXMRGFMSYEIC-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50277320
Affinity DataIC50: 250nMAssay Description:Inhibition of VEGFR1 (unknown origin) assessed as blockade of pGAT-biotin phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of VEGFR2 (unknown origin) assessed as blockade of pGAT-biotin phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of VEGFR2 (unknown origin) expressed in HEK293 cells assessed as inhibition of receptor phosphorylation by ELISAMore data for this Ligand-Target Pair