BDBM50277364 CHEMBL475708::N-(4-tert-butylphenyl)-4-(pyridin-4-ylmethylamino)isothiazole-3-carboxamide
SMILES CC(C)(C)c1ccc(NC(=O)c2nscc2NCc2ccncc2)cc1
InChI Key InChIKey=SLKBRIIMEDRSRH-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50277364
Affinity DataIC50: 610nMAssay Description:Inhibition of VEGFR1 (unknown origin) assessed as blockade of pGAT-biotin phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Inhibition of VEGFR2 (unknown origin) assessed as blockade of pGAT-biotin phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of VEGFR2 (unknown origin) expressed in HEK293 cells assessed as inhibition of receptor phosphorylation by ELISAMore data for this Ligand-Target Pair