BDBM50277433 CHEMBL473268::N-(4-chloro-3-(trifluoromethyl)phenyl)-4-(pyridin-4-ylmethylamino)isothiazole-3-carboxamide
SMILES FC(F)(F)c1cc(NC(=O)c2nscc2NCc2ccncc2)ccc1Cl
InChI Key InChIKey=LAUCIMWNCKMKNY-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50277433
Affinity DataIC50: 980nMAssay Description:Inhibition of VEGFR1 (unknown origin) assessed as blockade of pGAT-biotin phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of VEGFR2 (unknown origin) assessed as blockade of pGAT-biotin phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 530nMAssay Description:Inhibition of VEGFR2 (unknown origin) expressed in HEK293 cells assessed as inhibition of receptor phosphorylation by ELISAMore data for this Ligand-Target Pair