BDBM50277564 5-(6-amino-9-isobutyl-9H-purin-8-yl)furan-2-ylphosphonic acid::CHEMBL482734

SMILES CC(C)Cn1c(nc2c(N)ncnc12)-c1ccc(o1)P(O)(O)=O

InChI Key InChIKey=ALCWDDPQWXTHJP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50277564   

TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50277564(5-(6-amino-9-isobutyl-9H-purin-8-yl)furan-2-ylphos...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50277564(5-(6-amino-9-isobutyl-9H-purin-8-yl)furan-2-ylphos...)
Affinity DataIC50:  800nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Rattus norvegicus)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50277564(5-(6-amino-9-isobutyl-9H-purin-8-yl)furan-2-ylphos...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of rat liver FBPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50277564(5-(6-amino-9-isobutyl-9H-purin-8-yl)furan-2-ylphos...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human liver FBPase expressed in Escherichia coli by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed