BDBM50277816 3-methoxy-N-((S)-3-methoxy-1-((S)-3-methoxy-1-((S)-1-((R)-2-methyloxiran-2-yl)-1-oxo-3-phenylpropan-2-ylamino)-1-oxopropan-2-ylamino)-1-oxopropan-2-yl)isoxazole-5-carboxamide::CHEMBL483739

SMILES COC[C@H](NC(=O)[C@H](COC)NC(=O)c1cc(OC)no1)C(=O)N[C@@H](Cc1ccccc1)C(=O)[C@@]1(C)CO1

InChI Key InChIKey=KEQXNGHAMBTTQH-VQIKXDESSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50277816   

TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277816(3-methoxy-N-((S)-3-methoxy-1-((S)-3-methoxy-1-((S)...)
Affinity DataIC50:  36nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed