BDBM50277897 (2S)-2-methoxy-3-{4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-1-benzothiophen-7-yl}propanoic acid::Aleglitazar::CHEMBL519504

SMILES CO[C@@H](Cc1ccc(OCCc2nc(oc2C)-c2ccccc2)c2ccsc12)C(O)=O

InChI Key InChIKey=DAYKLWSKQJBGCS-NRFANRHFSA-N

Data  2 IC50  5 EC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50277897   

TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50277897((2S)-2-methoxy-3-{4-[2-(5-methyl-2-phenyl-1,3-oxaz...)
Affinity DataEC50:  53nMAssay Description:Agonist activity at PPARdelta (unknown origin) by luciferase reporter transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Rattus norvegicus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50277897((2S)-2-methoxy-3-{4-[2-(5-methyl-2-phenyl-1,3-oxaz...)
Affinity DataEC50:  2.26E+3nMAssay Description:Agonist activity at rat PPARalphaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50277897((2S)-2-methoxy-3-{4-[2-(5-methyl-2-phenyl-1,3-oxaz...)
Affinity DataEC50:  2.34E+3nMAssay Description:Agonist activity at mouse PPARalphaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50277897((2S)-2-methoxy-3-{4-[2-(5-methyl-2-phenyl-1,3-oxaz...)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human PPARgamma expressed in BHK21 cells assessed as SEAP activity by luciferase reporter transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50277897((2S)-2-methoxy-3-{4-[2-(5-methyl-2-phenyl-1,3-oxaz...)
Affinity DataIC50:  19nMAssay Description:Displacement of radio labeled 2(S)-(2-benzoyl-phenylamino)-3-{4-[1,1-ditritio-2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-propionic acid from G...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50277897((2S)-2-methoxy-3-{4-[2-(5-methyl-2-phenyl-1,3-oxaz...)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human PPARalpha by luciferase reporter transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50277897((2S)-2-methoxy-3-{4-[2-(5-methyl-2-phenyl-1,3-oxaz...)
Affinity DataIC50:  38nMAssay Description:Displacement of radio labeled 2(S)-(2-benzoyl-phenylamino)-3-{4-[1,1-ditritio-2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-propionic acid from G...More data for this Ligand-Target Pair