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BDBM50278193 3-(pyridin-3-yl)-1-(2,3,4-trimethoxyphenyl)prop-2-en-1-one::CHEMBL509932::WR-289013

SMILES: COc1ccc(C(=O)\C=C\c2cccnc2)c(OC)c1OC

InChI Key: InChIKey=QNSVIKWLSFHHDS-SOFGYWHQSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278193   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein kinase Pfmrk


(Plasmodium falciparum)
BDBM50278193
PNG
(3-(pyridin-3-yl)-1-(2,3,4-trimethoxyphenyl)prop-2-...)
Show SMILES COc1ccc(C(=O)\C=C\c2cccnc2)c(OC)c1OC
Show InChI InChI=1S/C17H17NO4/c1-20-15-9-7-13(16(21-2)17(15)22-3)14(19)8-6-12-5-4-10-18-11-12/h4-11H,1-3H3/b8-6+
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.80E+4n/an/an/an/an/an/a



Institute of Research

Curated by ChEMBL


Assay Description
Inhibition of His6x-tagged Plasmodium falciparum Pfmrk expressed in Escherichia coli by microtiter plate scintillation counting


Bioorg Med Chem Lett 19: 1982-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.042
BindingDB Entry DOI: 10.7270/Q2P26Z1T
More data for this
Ligand-Target Pair