BDBM50278521 (S)-N-butyl-N-(naphthalen-2-ylmethyl)pyrrolidin-3-amine::CHEMBL471029

SMILES CCCCN(Cc1ccc2ccccc2c1)[C@H]1CCNC1

InChI Key InChIKey=UAUSBXOENIHVFX-IBGZPJMESA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50278521   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50278521((S)-N-butyl-N-(naphthalen-2-ylmethyl)pyrrolidin-3-...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of radiolabeled serotonin reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50278521((S)-N-butyl-N-(naphthalen-2-ylmethyl)pyrrolidin-3-...)
Affinity DataIC50:  88nMAssay Description:Inhibition of radiolabeled dopamine reuptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50278521((S)-N-butyl-N-(naphthalen-2-ylmethyl)pyrrolidin-3-...)
Affinity DataIC50:  80nMAssay Description:Inhibition of radiolabeled noradrenaline reuptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed