BDBM50278810 CHEMBL4164428

SMILES [H][C@@]1(CC[C@@]2([H])C3=CC[C@@]4([H])C[C@H](CC[C@]4(C)[C@@]3([H])CC[C@]12C)OC(C)=O)[C@H](C)COC(=O)\C=C\C

InChI Key InChIKey=AORSDVNDRQVZPM-XXGPBDHDSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278810   

TargetDelta(24)-sterol reductase(Homo sapiens)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50278810(CHEMBL4164428)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of DHCR24-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate incorporation into newly synthesi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed