BDBM50279298 (Z)-3-({4-[2-(4-Methylpiperazin-1-yl)acetylamino]-phenylamino}-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylicAcidMethyl Ester::CHEMBL465015

SMILES COC(=O)c1ccc2C(C(=Nc3ccc(NC(=O)CN4CCN(C)CC4)cc3)c3ccccc3)C(=O)Nc2c1

InChI Key InChIKey=HPTYEEJJIBEOEW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50279298   

TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279298((Z)-3-({4-[2-(4-Methylpiperazin-1-yl)acetylamino]-...)
Affinity DataIC50:  278nMAssay Description:Inhibition of human VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279298((Z)-3-({4-[2-(4-Methylpiperazin-1-yl)acetylamino]-...)
Affinity DataIC50:  24nMAssay Description:Inhibition of human VEGFR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279298((Z)-3-({4-[2-(4-Methylpiperazin-1-yl)acetylamino]-...)
Affinity DataIC50:  219nMAssay Description:Inhibition of human FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279298((Z)-3-({4-[2-(4-Methylpiperazin-1-yl)acetylamino]-...)
Affinity DataIC50:  83nMAssay Description:Inhibition of human VEGFR2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279298((Z)-3-({4-[2-(4-Methylpiperazin-1-yl)acetylamino]-...)
Affinity DataIC50:  164nMAssay Description:Inhibition of human PDGFRalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed