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BDBM50279433 1-(2,3-dihydro-6-hydroxychromen-4-ylideneamino)-3-(4-(piperidin-1-yl)butyl)imidazolidine-2,4-dione::CHEMBL518885

SMILES: Oc1cn(N=C2CCOc3ccc(O)cc23)c(=O)n1CCCCN1CCCCC1

InChI Key: InChIKey=HMOWTTBQYMPNBO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50279433   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium voltage-gated channel subfamily H member 2


(Cavia porcellus)
BDBM50279433
PNG
(1-(2,3-dihydro-6-hydroxychromen-4-ylideneamino)-3-...)
Show SMILES Oc1cn(N=C2CCOc3ccc(O)cc23)c(=O)n1CCCCN1CCCCC1
Show InChI InChI=1S/C21H28N4O4/c26-16-6-7-19-17(14-16)18(8-13-29-19)22-25-15-20(27)24(21(25)28)12-5-4-11-23-9-2-1-3-10-23/h6-7,14-15,26-27H,1-5,8-13H2
UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of ERG in guinea pig ventricular myocytes assessed as blockade of rapid delayed rectifier potassium current by whole cell patch-clamp tech...


Bioorg Med Chem Lett 19: 1477-80 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.022
BindingDB Entry DOI: 10.7270/Q22J6BQK
More data for this
Ligand-Target Pair
Voltage-gated potassium channel subunit Kv7.1


(Cavia porcellus)
BDBM50279433
PNG
(1-(2,3-dihydro-6-hydroxychromen-4-ylideneamino)-3-...)
Show SMILES Oc1cn(N=C2CCOc3ccc(O)cc23)c(=O)n1CCCCN1CCCCC1
Show InChI InChI=1S/C21H28N4O4/c26-16-6-7-19-17(14-16)18(8-13-29-19)22-25-15-20(27)24(21(25)28)12-5-4-11-23-9-2-1-3-10-23/h6-7,14-15,26-27H,1-5,8-13H2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 5.40E+3n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...


Bioorg Med Chem Lett 19: 1477-80 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.022
BindingDB Entry DOI: 10.7270/Q22J6BQK
More data for this
Ligand-Target Pair