BDBM50279593 CHEMBL4168811

SMILES COC(=O)c1ccc2\C(=C(\Nc3ccc4CCN(C(=O)CN5CCOCC5)c4c3)c3ccccc3)C(=O)Nc2c1

InChI Key InChIKey=FGFZBTQWDLZHSI-ZIADKAODSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50279593   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279593(CHEMBL4168811)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant c-KIT (unknown origin) by off-chip mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279593(CHEMBL4168811)
Affinity DataIC50:  110nMAssay Description:Inhibition of recombinant VEGFR2 (unknown origin) by off-chip mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279593(CHEMBL4168811)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of recombinant FGFR1 (unknown origin) by off-chip mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279593(CHEMBL4168811)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of recombinant RET (unknown origin) by off-chip mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279593(CHEMBL4168811)
Affinity DataIC50: >30nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279593(CHEMBL4168811)
Affinity DataIC50:  100nMAssay Description:Inhibition of PDGFR in mouse NIH/3T3 cells assessed as reduction in recombinant human PDGF-BB-induced cell proliferation after 42 hrs by cell titer 9...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279593(CHEMBL4168811)
Affinity DataIC50:  25nMAssay Description:H1-antihistamine activity on guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed