BDBM50279595 CHEMBL4165455

SMILES COC(=O)c1ccc2\C(=C(\Nc3ccc4CCN(C(=O)CN5CCCC5=O)c4c3)c3ccccc3)C(=O)Nc2c1

InChI Key InChIKey=LRNXJAKOQFCAJB-ZIADKAODSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50279595   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279595(CHEMBL4165455)
Affinity DataIC50: >30nMAssay Description:Inhibition of dihydrofolate reductase in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279595(CHEMBL4165455)
Affinity DataIC50:  230nMAssay Description:Inhibition of recombinant VEGFR2 (unknown origin) by off-chip mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279595(CHEMBL4165455)
Affinity DataIC50:  260nMAssay Description:Inhibition constant against Bacillus subtilis azp-12 DNA topoisomerase III (mutant enzyme).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279595(CHEMBL4165455)
Affinity DataIC50:  19nMAssay Description:Inhibition of recombinant PDGFRbeta (unknown origin) by off-chip mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279595(CHEMBL4165455)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of recombinant FGFR1 (unknown origin) by off-chip mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed