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BDBM50279719 1-(2,3-dihydro-6-amidecarboxylchromen-4-ylideneamino)-3-(4-(4-methylpiperazin-1-yl)butyl)imidazolidine-2,4-dione::CHEMBL474106

SMILES: CN1CCN(CCCCn2c(O)cn(N=C3CCOc4ccc(cc34)C(N)=O)c2=O)CC1

InChI Key: InChIKey=SGUPDGNXFUXPGW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50279719   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium voltage-gated channel subfamily H member 2


(Cavia porcellus)
BDBM50279719
PNG
(1-(2,3-dihydro-6-amidecarboxylchromen-4-ylideneami...)
Show SMILES CN1CCN(CCCCn2c(O)cn(N=C3CCOc4ccc(cc34)C(N)=O)c2=O)CC1
Show InChI InChI=1S/C22H30N6O4/c1-25-9-11-26(12-10-25)7-2-3-8-27-20(29)15-28(22(27)31)24-18-6-13-32-19-5-4-16(21(23)30)14-17(18)19/h4-5,14-15,29H,2-3,6-13H2,1H3,(H2,23,30)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 450n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of ERG in guinea pig ventricular myocytes assessed as blockade of rapid delayed rectifier potassium current by whole cell patch-clamp tech...


Bioorg Med Chem Lett 19: 1477-80 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.022
BindingDB Entry DOI: 10.7270/Q22J6BQK
More data for this
Ligand-Target Pair
Voltage-gated potassium channel subunit Kv7.1


(Cavia porcellus)
BDBM50279719
PNG
(1-(2,3-dihydro-6-amidecarboxylchromen-4-ylideneami...)
Show SMILES CN1CCN(CCCCn2c(O)cn(N=C3CCOc4ccc(cc34)C(N)=O)c2=O)CC1
Show InChI InChI=1S/C22H30N6O4/c1-25-9-11-26(12-10-25)7-2-3-8-27-20(29)15-28(22(27)31)24-18-6-13-32-19-5-4-16(21(23)30)14-17(18)19/h4-5,14-15,29H,2-3,6-13H2,1H3,(H2,23,30)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 330n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...


Bioorg Med Chem Lett 19: 1477-80 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.022
BindingDB Entry DOI: 10.7270/Q22J6BQK
More data for this
Ligand-Target Pair