BindingDB logo
myBDB logout

BDBM50279738 1-(2,3-dihydro-6-methoxychromen-4-ylideneamino)-3-(4-(piperidin-1-yl)butyl)imidazolidine-2,4-dione::CHEMBL475723

SMILES: COc1ccc2OCCC(=Nn3cc(O)n(CCCCN4CCCCC4)c3=O)c2c1

InChI Key: InChIKey=UGNRGLDJHAEIHL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50279738   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated potassium channel subunit Kv7.1


(Cavia porcellus)
BDBM50279738
PNG
(1-(2,3-dihydro-6-methoxychromen-4-ylideneamino)-3-...)
Show SMILES COc1ccc2OCCC(=Nn3cc(O)n(CCCCN4CCCCC4)c3=O)c2c1
Show InChI InChI=1S/C22H30N4O4/c1-29-17-7-8-20-18(15-17)19(9-14-30-20)23-26-16-21(27)25(22(26)28)13-6-5-12-24-10-3-2-4-11-24/h7-8,15-16,27H,2-6,9-14H2,1H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.20E+4n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...


Bioorg Med Chem Lett 19: 1477-80 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.022
BindingDB Entry DOI: 10.7270/Q22J6BQK
More data for this
Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2


(Cavia porcellus)
BDBM50279738
PNG
(1-(2,3-dihydro-6-methoxychromen-4-ylideneamino)-3-...)
Show SMILES COc1ccc2OCCC(=Nn3cc(O)n(CCCCN4CCCCC4)c3=O)c2c1
Show InChI InChI=1S/C22H30N4O4/c1-29-17-7-8-20-18(15-17)19(9-14-30-20)23-26-16-21(27)25(22(26)28)13-6-5-12-24-10-3-2-4-11-24/h7-8,15-16,27H,2-6,9-14H2,1H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 7.47E+3n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of ERG in guinea pig ventricular myocytes assessed as blockade of rapid delayed rectifier potassium current by whole cell patch-clamp tech...


Bioorg Med Chem Lett 19: 1477-80 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.022
BindingDB Entry DOI: 10.7270/Q22J6BQK
More data for this
Ligand-Target Pair