BDBM50279755 7-Phenyl-7-(2,4,5-trimethyl-3,6-dioxo-cyclohexa-1,4-dienyl)-heptanoic acid::CHEMBL70972::Seratrodast

SMILES Cc1c(C)c(O)c(C(=CCCCCC(O)=O)c2ccccc2)c(C)c1O

InChI Key InChIKey=RADRBZBLNXVQEU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50279755   

TargetBile salt export pump(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50279755(7-Phenyl-7-(2,4,5-trimethyl-3,6-dioxo-cyclohexa-1,...)
Affinity DataIC50: <1.43E+4nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50279755(7-Phenyl-7-(2,4,5-trimethyl-3,6-dioxo-cyclohexa-1,...)
Affinity DataIC50:  7.40nMAssay Description:In vitro concentration of the compound that reduced specific binding of [3H]-U-440619 to guinea pig platelet receptor, TXA2 by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed