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BDBM50280292 7-[3-(2-Ethyl-5-hydroxy-4-methoxy-phenoxy)-propoxy]-8-propyl-chroman-2-carboxylic acid::CHEMBL294987

SMILES: CCCc1c(OCCCOc2cc(O)c(OC)cc2CC)ccc2CCC(Oc12)C(O)=O

InChI Key: InChIKey=PSTYZGXBVHSCTQ-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50280292   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Leukotriene B4 receptor


(HUMAN)
BDBM50280292
PNG
(7-[3-(2-Ethyl-5-hydroxy-4-methoxy-phenoxy)-propoxy...)
Show SMILES CCCc1c(OCCCOc2cc(O)c(OC)cc2CC)ccc2CCC(Oc12)C(O)=O
Show InChI InChI=1S/C25H32O7/c1-4-7-18-20(10-8-17-9-11-21(25(27)28)32-24(17)18)30-12-6-13-31-22-15-19(26)23(29-3)14-16(22)5-2/h8,10,14-15,21,26H,4-7,9,11-13H2,1-3H3,(H,27,28)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
n/an/a 2.90n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity using [3H]-LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assay


Bioorg Med Chem Lett 2: 1675-1680 (1992)


Article DOI: 10.1016/S0960-894X(00)80454-0
BindingDB Entry DOI: 10.7270/Q2JW8DT9
More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50280292
PNG
(7-[3-(2-Ethyl-5-hydroxy-4-methoxy-phenoxy)-propoxy...)
Show SMILES CCCc1c(OCCCOc2cc(O)c(OC)cc2CC)ccc2CCC(Oc12)C(O)=O
Show InChI InChI=1S/C25H32O7/c1-4-7-18-20(10-8-17-9-11-21(25(27)28)32-24(17)18)30-12-6-13-31-22-15-19(26)23(29-3)14-16(22)5-2/h8,10,14-15,21,26H,4-7,9,11-13H2,1-3H3,(H,27,28)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
1.90n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity using [3H]-LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assay


Bioorg Med Chem Lett 2: 1675-1680 (1992)


Article DOI: 10.1016/S0960-894X(00)80454-0
BindingDB Entry DOI: 10.7270/Q2JW8DT9
More data for this
Ligand-Target Pair