BDBM50280372 CHEMBL4165849

SMILES COc1cc(ccc1OC(C)C)C(=O)Nc1cc(OC(F)(F)F)ccc1-n1cncn1

InChI Key InChIKey=PLBFRTZUKAUTAA-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50280372   

TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50280372(CHEMBL4165849)
Affinity DataIC50:  780nMAssay Description:In vitro inhibitory activity against angiotensin I converting enzyme of rats.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50280372(CHEMBL4165849)
Affinity DataIC50:  776nMAssay Description:In vitro inhibitory activity against angiotensin I converting enzyme of rats.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50280372(CHEMBL4165849)
Affinity DataIC50:  5.01E+3nMAssay Description:Negative allosteric modulation of mGlu7 (unknown origin) in cells expressing G protein-regulated inwardly rectifying potassium channels (GIRKs) asses...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50280372(CHEMBL4165849)
Affinity DataIC50:  890nMAssay Description:Negative allosteric modulation of rat mGlu7 in HEK cells expressing Galpha15 assessed as inhibition of L-AP4-induced response measured by calcium mob...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50280372(CHEMBL4165849)
Affinity DataIC50:  5.20E+3nMAssay Description:Negative allosteric modulation of mGlu7 (unknown origin) in cells expressing G protein-regulated inwardly rectifying potassium channels (GIRKs) asses...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50280372(CHEMBL4165849)
Affinity DataIC50:  890nMAssay Description:Negative allosteric modulation of rat mGlu7 in HEK cells expressing Galpha15 assessed as inhibition of L-AP4-induced response measured by calcium mob...More data for this Ligand-Target Pair
In DepthDetails PubMed