BDBM50282396 (S)-1-(4-Dimethylamino-3-methyl-benzyl)-5-diphenylacetyl-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid::CHEMBL157946::PD-123319

SMILES CN(C)c1ccc(Cn2cnc3CN([C@@H](Cc23)C(O)=O)C(=O)C(c2ccccc2)c2ccccc2)cc1C

InChI Key InChIKey=YSTVFDAKLDMYCR-NDEPHWFRSA-N

Data  3 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50282396   

TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (Chuv) And University Of Lausanne (Unil

Curated by ChEMBL
LigandPNGBDBM50282396((S)-1-(4-Dimethylamino-3-methyl-benzyl)-5-diphenyl...)
Affinity DataKi:  12nMAssay Description:Inhibition of human AT1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Sus scrofa)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50282396((S)-1-(4-Dimethylamino-3-methyl-benzyl)-5-diphenyl...)
Affinity DataKi:  34nMAssay Description:Displacement of [125I]angiotensin 2 from AT2 receptor in pig uterus membrane after 1.5 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (Chuv) And University Of Lausanne (Unil

Curated by ChEMBL
LigandPNGBDBM50282396((S)-1-(4-Dimethylamino-3-methyl-benzyl)-5-diphenyl...)
Affinity DataKi:  1.20E+5nMAssay Description:Inhibition of human AT2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(RAT)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50282396((S)-1-(4-Dimethylamino-3-methyl-benzyl)-5-diphenyl...)
Affinity DataIC50:  34nMAssay Description:Inhibitory activity at Angiotensin II type 2 receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50282396((S)-1-(4-Dimethylamino-3-methyl-benzyl)-5-diphenyl...)
Affinity DataIC50:  34nMAssay Description:Binding affinity against Angiotensin II receptor, from rat adrenal glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50282396((S)-1-(4-Dimethylamino-3-methyl-benzyl)-5-diphenyl...)
Affinity DataIC50:  210nMAssay Description:Binding affinity for rat brain Angiotensin II receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (Chuv) And University Of Lausanne (Unil

Curated by ChEMBL
LigandPNGBDBM50282396((S)-1-(4-Dimethylamino-3-methyl-benzyl)-5-diphenyl...)
Affinity DataIC50:  6.90nMAssay Description:In vitro binding affinity of compound was measured against angiotensin II (AT2) receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (Chuv) And University Of Lausanne (Unil

Curated by ChEMBL
LigandPNGBDBM50282396((S)-1-(4-Dimethylamino-3-methyl-benzyl)-5-diphenyl...)
Affinity DataIC50:  8.30nMAssay Description:The compound was evaluated for the inhibition of binding of [125I]-CGP 42112A to AT2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (Chuv) And University Of Lausanne (Unil

Curated by ChEMBL
LigandPNGBDBM50282396((S)-1-(4-Dimethylamino-3-methyl-benzyl)-5-diphenyl...)
Affinity DataIC50:  6.90nMAssay Description:Inhibitory activity against angiotensin II type 2 (AT2) receptor in rabbit uterine membranes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (Chuv) And University Of Lausanne (Unil

Curated by ChEMBL
LigandPNGBDBM50282396((S)-1-(4-Dimethylamino-3-methyl-benzyl)-5-diphenyl...)
Affinity DataIC50:  34nMAssay Description:Displacement of [125I]-Ang II from pig uterus membrane angiotensin II type 2 (AT2) receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed