BDBM50282869 4-(1-Ethyl-propyl)-1,1-dioxo-2-(1-phenyl-1H-tetrazol-5-ylsulfanylmethyl)-1,2-dihydro-1lambda*6*-benzo[d]isothiazol-3-one::CHEMBL298107

SMILES CCC(CC)c1cccc2c1C(=O)N(CSc1nnnn1-c1ccccc1)S2(=O)=O

InChI Key InChIKey=MBXYNQQKHQJJGU-UHFFFAOYSA-N

Data  4 KI  1 Koff  4 Kon

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50282869   

TargetNeutrophil elastase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282869(4-(1-Ethyl-propyl)-1,1-dioxo-2-(1-phenyl-1H-tetraz...)
Affinity DataKi:  60nMAssay Description:Potency of Inhibition of human leukocyte elastase (HLE) expressed as apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282869(4-(1-Ethyl-propyl)-1,1-dioxo-2-(1-phenyl-1H-tetraz...)
Affinity DataKi:  60nMAssay Description:Ratio of Koff to that of Kon was determined on human leukocyte elastase(HLE)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282869(4-(1-Ethyl-propyl)-1,1-dioxo-2-(1-phenyl-1H-tetraz...)
Affinity DataKi:  60nM Koff:  4.40E+3s-1Assay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50282869(4-(1-Ethyl-propyl)-1,1-dioxo-2-(1-phenyl-1H-tetraz...)
Affinity DataKi: >1.50E+3nMAssay Description:Apparent binding constant Ki=Kon/KoffMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282869(4-(1-Ethyl-propyl)-1,1-dioxo-2-(1-phenyl-1H-tetraz...)
Affinity DataKoff:  4.40E+3s-1Assay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282869(4-(1-Ethyl-propyl)-1,1-dioxo-2-(1-phenyl-1H-tetraz...)
Affinity DataKoff:  4.40E+3s-1Assay Description:Inhibition of human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282869(4-(1-Ethyl-propyl)-1,1-dioxo-2-(1-phenyl-1H-tetraz...)
Affinity DataKon:  0.000260M-1s-1 Koff:  4.40E+3s-1Assay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails Article