BDBM50283310 4'-[2-Ethyl-6-(3-isopropyl-3-methyl-ureido)-4-oxo-4H-quinazolin-3-ylmethyl]-3'-fluoro-biphenyl-2-sulfonic acid 4-ethyl-benzoylamide::CHEMBL263452

SMILES CCc1ccc(cc1)C(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CC)nc3ccc(NC(=O)N(C)C(C)C)cc3c2=O)c(F)c1

InChI Key InChIKey=QZIPHSUNTJRFMC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50283310   

TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283310(4'-[2-Ethyl-6-(3-isopropyl-3-methyl-ureido)-4-oxo-...)
Affinity DataIC50:  0.25nMAssay Description:In vivo inhibitory concentration of the compound against Angiotensin II, type 2 of rat midbrain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283310(4'-[2-Ethyl-6-(3-isopropyl-3-methyl-ureido)-4-oxo-...)
Affinity DataIC50:  5.80nMAssay Description:In vivo inhibitory concentration of the compound against Angiotensin II receptor, type 1 of human adrenal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50283310(4'-[2-Ethyl-6-(3-isopropyl-3-methyl-ureido)-4-oxo-...)
Affinity DataIC50:  0.140nMAssay Description:In vivo inhibitory concentration of the compound against Angiotensin II, type 2 of rat midbrain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283310(4'-[2-Ethyl-6-(3-isopropyl-3-methyl-ureido)-4-oxo-...)
Affinity DataIC50:  0.540nMAssay Description:In vivo inhibitory concentration of the compound against Angiotensin II receptor, type 1 of rabbit aorta membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283310(4'-[2-Ethyl-6-(3-isopropyl-3-methyl-ureido)-4-oxo-...)
Affinity DataIC50:  0.930nMAssay Description:In vivo inhibitory concentration of the compound against AT2 receptor of rat adrenal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283310(4'-[2-Ethyl-6-(3-isopropyl-3-methyl-ureido)-4-oxo-...)
Affinity DataIC50:  8.90nMAssay Description:In vivo inhibitory concentration of the compound against AT2 receptor of human adrenal membraneMore data for this Ligand-Target Pair
In DepthDetails Article