BDBM50283487 CHEMBL4162576

SMILES Clc1ccc(Oc2ccc(NC(=O)c3ccccn3)cc2Cl)nc1

InChI Key InChIKey=MZRLPXFGQKQHST-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50283487   

TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283487(CHEMBL4162576)
Affinity DataEC50:  108nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in glutamate-induced calcium mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283487(CHEMBL4162576)
Affinity DataEC50:  125nMAssay Description:Positive allosteric modulation of rat mGlu8 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283487(CHEMBL4162576)
Affinity DataEC50:  146nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed