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BDBM50283498 4-[1-Furan-2-yl-meth-(Z)-ylidene]-3-phenyl-4H-isoxazol-5-one::CHEMBL80658::cid_1834885

SMILES: O=C1ON=C(\C1=C\c1ccco1)c1ccccc1

InChI Key: InChIKey=XHXFSCFVKOCKSR-XFXZXTDPSA-N

Data: 1 IC50  1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50283498   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase


(Yersinia pestis)
BDBM50283498
PNG
(4-[1-Furan-2-yl-meth-(Z)-ylidene]-3-phenyl-4H-isox...)
Show SMILES O=C1ON=C(\C1=C\c1ccco1)c1ccccc1
Show InChI InChI=1S/C14H9NO3/c16-14-12(9-11-7-4-8-17-11)13(15-18-14)10-5-2-1-3-6-10/h1-9H/b12-9-
KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

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Similars

Article
PubMed
n/an/a 1.20E+4n/an/an/an/an/an/a



University of Utah

Curated by ChEMBL


Assay Description
Inhibition of His6-tagged Yersinia pestis KIM6 CDP-ME kinase assessed as ADP production after 30 mins by Kinase Glo luminescence-based assay or stand...


Bioorg Med Chem 19: 5886-95 (2011)


Article DOI: 10.1016/j.bmc.2011.08.012
BindingDB Entry DOI: 10.7270/Q2W37WQJ
More data for this
Ligand-Target Pair
LAP4


(Saccharomyces cerevisiae)
BDBM50283498
PNG
(4-[1-Furan-2-yl-meth-(Z)-ylidene]-3-phenyl-4H-isox...)
Show SMILES O=C1ON=C(\C1=C\c1ccco1)c1ccccc1
Show InChI InChI=1S/C14H9NO3/c16-14-12(9-11-7-4-8-17-11)13(15-18-14)10-5-2-1-3-6-10/h1-9H/b12-9-
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

n/an/an/an/a 4.26E+3n/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q21R6P02
More data for this
Ligand-Target Pair