BDBM50283972 CHEMBL4162565

SMILES Cn1ncc2CN(C(=O)Cc3cccc(c3)N3CCN(Cc4cc(O)cc(O)c4)CC3)c3ccccc3Nc12

InChI Key InChIKey=DJFQESWUILRMGI-UHFFFAOYSA-N

Data  2 KI  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50283972   

TargetVasopressin V1a receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50283972(CHEMBL4162565)
Affinity DataKi:  643nMAssay Description:Displacement of [3H]-vasopressin from human vasopressin V1a receptor expressed in HEK293 cell membranes after 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50283972(CHEMBL4162565)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-oxytocin from human OTR expressed in HEK293 cell membranes after 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50283972(CHEMBL4162565)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human OTR expressed in HEK293 cells assessed as induction of IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50283972(CHEMBL4162565)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human vasopressin V1a receptor expressed in HEK293 cells assessed as induction of IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50283972(CHEMBL4162565)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human OTR expressed in HEK293 cells assessed as inhibition of agonist-induced IP1 accumulation preincubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50283972(CHEMBL4162565)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human vasopressin V1a receptor expressed in HEK293 cells assessed as inhibition of vasopressin-induced IP1 accumulation preinc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed