BDBM50287949 1-[(2R,6S)-4-Benzenesulfonyl-6-(tert-butyl-dimethyl-silanyloxymethyl)-morpholin-2-yl]-4-chloro-6-methoxy-3-methyl-1H-pyrazolo[3,4-b]quinoline::CHEMBL432297

SMILES COc1ccc2nc3n(nc(C)c3c(Cl)c2c1)[C@H]1CN(C[C@@H](CO[Si](C)(C)C(C)(C)C)O1)S(=O)(=O)c1ccccc1

InChI Key InChIKey=GULGEVVCYKRKLR-SQJMNOBHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50287949   

TargetGTPase HRas(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287949(1-[(2R,6S)-4-Benzenesulfonyl-6-(tert-butyl-dimethy...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
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