BDBM50288821 (S)-2-{(S)-4-[3-(2,4-Diamino-pyrimidin-5-yl)-propyl]-benzoylamino}-pentanedioic acid::CHEMBL443763::LY-316373

SMILES Nc1ncc(CCCc2ccc(cc2)C(=O)N[C@@H](CCC(O)=O)C(O)=O)c(N)n1

InChI Key InChIKey=BGHRPMFGMOHAJK-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50288821   

TargetDihydrofolate reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288821((S)-2-{(S)-4-[3-(2,4-Diamino-pyrimidin-5-yl)-propy...)
Affinity DataKi:  0.120nMAssay Description:Binding affinity of the compound against Recombinant human dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails Article
TargetThymidylate synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288821((S)-2-{(S)-4-[3-(2,4-Diamino-pyrimidin-5-yl)-propy...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity of the compound against Recombinant human thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails Article