BDBM50289136 6-Fluoro-3-((E)-2-pyridin-4-yl-vinyl)-1H-indole::CHEMBL435072

SMILES Fc1ccc2c(\C=C\c3ccncc3)c[nH]c2c1

InChI Key InChIKey=UJTBWNKRXRHIGU-OWOJBTEDSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289136   

TargetTryptophan 2,3-dioxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50289136(6-Fluoro-3-((E)-2-pyridin-4-yl-vinyl)-1H-indole | ...)
Affinity DataKi:  30nMAssay Description:Compound was tested for inhibition of Tryptophan dioxygenase (TDO) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
TargetTryptophan 2,3-dioxygenase(Mus musculus)
University Of Namur

Curated by ChEMBL
LigandPNGBDBM50289136(6-Fluoro-3-((E)-2-pyridin-4-yl-vinyl)-1H-indole | ...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed