BDBM50290634 (6,7-Dimethoxy-quinazolin-4-yl)-isoquinolin-3-yl-amine::CHEMBL91428

SMILES COc1cc2ncnc(Nc3cc4ccccc4cn3)c2cc1OC

InChI Key InChIKey=TWVXDJSEKDRXKV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50290634   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290634((6,7-Dimethoxy-quinazolin-4-yl)-isoquinolin-3-yl-a...)
Affinity DataIC50:  810nMAssay Description:Inhibition of EGF-stimulated proliferation of KB cells in cultureMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290634((6,7-Dimethoxy-quinazolin-4-yl)-isoquinolin-3-yl-a...)
Affinity DataIC50:  660nMAssay Description:Tested for inhibition of Epidermal growth factor receptor from A431 vulval squamous carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails Article