BDBM50291511 2-((E)-3-Biphenyl-4-yl-acryloylamino)-benzoic acid::CHEMBL176974

SMILES OC(=O)c1ccccc1NC(=O)\C=C\c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=AIGCPSYTABFABO-NTCAYCPXSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50291511   

LigandPNGBDBM50291511(2-((E)-3-Biphenyl-4-yl-acryloylamino)-benzoic acid...)
Affinity DataIC50:  2.56E+3nMAssay Description:Inhibition of human TRPM2 expressed in HEK293T cells assessed as blocked of ADPR-activated current by whole cell patch clamp electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLeukotriene B4 receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291511(2-((E)-3-Biphenyl-4-yl-acryloylamino)-benzoic acid...)
Affinity DataIC50:  830nMAssay Description:In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]-LTB4 from isolated neutrophilsMore data for this Ligand-Target Pair
In DepthDetails Article