BDBM50291803 1-(3-Dodecyl-phenyl)-6,6-dimethyl-1,6-dihydro-[1,3,5]triazine-2,4-diamine::CHEMBL21254

SMILES CCCCCCCCCCCCc1cccc(c1)N1C(N)=NC(N)=NC1(C)C

InChI Key InChIKey=ZDOWVJFTJBBSAO-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50291803   

TargetDihydrofolate reductase(Escherichia coli)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50291803(1-(3-Dodecyl-phenyl)-6,6-dimethyl-1,6-dihydro-[1,3...)
Affinity DataKi:  12.6nMAssay Description:Inhibition of dihydrofolate reductase from Pneumocystis carinii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50291803(1-(3-Dodecyl-phenyl)-6,6-dimethyl-1,6-dihydro-[1,3...)
Affinity DataKi:  72.4nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from Leishmania majorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50291803(1-(3-Dodecyl-phenyl)-6,6-dimethyl-1,6-dihydro-[1,3...)
Affinity DataKi:  302nMAssay Description:Inhibition of human dihydrofolate reductase (DHFR) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
TBA

Curated by ChEMBL
LigandPNGBDBM50291803(1-(3-Dodecyl-phenyl)-6,6-dimethyl-1,6-dihydro-[1,3...)
Affinity DataKi:  417nMAssay Description:Inhibitory activity against isolated chicken liver dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50291803(1-(3-Dodecyl-phenyl)-6,6-dimethyl-1,6-dihydro-[1,3...)
Affinity DataKi:  2.14E+3nMAssay Description:Inhibitory activity against Lactobacillus casei dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed