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BDBM50291990 (R)-2-Amino-N-(2,6-dimethyl-phenyl)-propionamide(tocainide)::(R)-2-amino-N-(2,6-dimethylphenyl)propanamide::2-Amino-N-(2,6-dimethyl-phenyl)-propionamide::CHEMBL222944::TOCAINIDE::Tonocard::W-36095

SMILES: C[C@@H](N)C(=O)Nc1c(C)cccc1C

InChI Key: InChIKey=BUJAGSGYPOAWEI-SECBINFHSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50291990   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated sodium channel subunit alpha Nav1.4 (Nav1.4)


(Homo sapiens (Human))
BDBM50291990
PNG
((R)-2-Amino-N-(2,6-dimethyl-phenyl)-propionamide(t...)
Show SMILES C[C@@H](N)C(=O)Nc1c(C)cccc1C
Show InChI InChI=1S/C11H16N2O/c1-7-5-4-6-8(2)10(7)13-11(14)9(3)12/h4-6,9H,12H2,1-3H3,(H,13,14)/t9-/m1/s1
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2.75E+5n/an/an/an/a



Universit£ degli Studi di Bari

Curated by ChEMBL


Assay Description
Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium current


Eur J Med Chem 44: 1477-85 (2009)

More data for this
Ligand-Target Pair