BDBM50292637 (+)-1'-(4-bromobenzyl)-3-(2,4-difluorophenyl)-3,4'-bipiperidine-2,6-dione::(+/-)-1'-(4-bromobenzyl)-3-(2,4-difluorophenyl)-3,4'-bipiperidine-2,6-dione::(-)-1'-(4-bromobenzyl)-3-(2,4-difluorophenyl)-3,4'-bipiperidine-2,6-dione::CHEMBL495531

SMILES Fc1ccc(c(F)c1)C1(CCC(=O)NC1=O)C1CCN(Cc2ccc(Br)cc2)CC1

InChI Key InChIKey=BJFMBQBPMWUGFF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50292637   

TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292637((+)-1'-(4-bromobenzyl)-3-(2,4-difluorophenyl)-3,4'...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to human muscarinic M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292637((+)-1'-(4-bromobenzyl)-3-(2,4-difluorophenyl)-3,4'...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to human muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292637((+)-1'-(4-bromobenzyl)-3-(2,4-difluorophenyl)-3,4'...)
Affinity DataIC50:  60nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292637((+)-1'-(4-bromobenzyl)-3-(2,4-difluorophenyl)-3,4'...)
Affinity DataIC50:  120nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292637((+)-1'-(4-bromobenzyl)-3-(2,4-difluorophenyl)-3,4'...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to human muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292637((+)-1'-(4-bromobenzyl)-3-(2,4-difluorophenyl)-3,4'...)
Affinity DataIC50:  120nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed