BDBM50292638 (+)-1'-(4-bromobenzyl)-N,3-diphenyl-3,4'-bipiperidine-1-carboxamide::(+/-)-1'-(4-bromobenzyl)-N,3-diphenyl-3,4'-bipiperidine-1-carboxamide::(-)-1'-(4-bromobenzyl)-N,3-diphenyl-3,4'-bipiperidine-1-carboxamide::CHEMBL497799

SMILES Brc1ccc(CN2CCC(CC2)C2(CCCN(C2)C(=O)Nc2ccccc2)c2ccccc2)cc1

InChI Key InChIKey=WSPJCXDAFUSHQL-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50292638   

TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292638((+)-1'-(4-bromobenzyl)-N,3-diphenyl-3,4'-bipiperid...)
Affinity DataIC50:  8.90E+3nMAssay Description:Binding affinity to human muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292638((+)-1'-(4-bromobenzyl)-N,3-diphenyl-3,4'-bipiperid...)
Affinity DataIC50:  60nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292638((+)-1'-(4-bromobenzyl)-N,3-diphenyl-3,4'-bipiperid...)
Affinity DataIC50:  60nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292638((+)-1'-(4-bromobenzyl)-N,3-diphenyl-3,4'-bipiperid...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to human muscarinic M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292638((+)-1'-(4-bromobenzyl)-N,3-diphenyl-3,4'-bipiperid...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to human muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292638((+)-1'-(4-bromobenzyl)-N,3-diphenyl-3,4'-bipiperid...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to human muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50292638((+)-1'-(4-bromobenzyl)-N,3-diphenyl-3,4'-bipiperid...)
Affinity DataIC50:  6.31E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed