BDBM50293174 (trans)-N1-(5-((5-tert-butyloxazol-2-yl)methylthio)thiazol-2-yl)cyclohexane-1,4-diamine::CHEMBL496567
SMILES CC(C)(C)c1cnc(CSc2cnc(N[C@H]3CC[C@H](N)CC3)s2)o1
InChI Key InChIKey=JFSGUSJACVSEKX-HAQNSBGRSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50293174
Affinity DataIC50: 355nMAssay Description:Inhibition of CDK9 in human HCT116 cells assessed as phosphor-ser2 level of RNA polymerase 2 after 16 hrs by high content cellular assayMore data for this Ligand-Target Pair
Affinity DataIC50: 763nMAssay Description:Inhibition of CDK1/cyclin B by IMAP florescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of CDK2/cyclin A by IMAP florescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 105nMAssay Description:Inhibition of CDK7/cyclinH by IMAP florescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 97nMAssay Description:Inhibition of CDK9/cyclinT by IMAP florescence polarization assayMore data for this Ligand-Target Pair