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BDBM50293719 CHEMBL571453::N-(3-(trifluoromethyl)phenyl)picolinamide::cid_2306530

SMILES: FC(F)(F)c1cccc(NC(=O)c2ccccn2)c1

InChI Key: InChIKey=QJUCVRVRFWBVTF-UHFFFAOYSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50293719   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 4 (mGluR4)


(Homo sapiens (Human))
BDBM50293719
PNG
(CHEMBL571453 | N-(3-(trifluoromethyl)phenyl)picoli...)
Show SMILES FC(F)(F)c1cccc(NC(=O)c2ccccn2)c1
Show InChI InChI=1S/C13H9F3N2O/c14-13(15,16)9-4-3-5-10(8-9)18-12(19)11-6-1-2-7-17-11/h1-8H,(H,18,19)
UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

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PCBioAssay
n/an/an/an/a 3.55E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2VT1QHF
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGluR4)


(Homo sapiens (Human))
BDBM50293719
PNG
(CHEMBL571453 | N-(3-(trifluoromethyl)phenyl)picoli...)
Show SMILES FC(F)(F)c1cccc(NC(=O)c2ccccn2)c1
Show InChI InChI=1S/C13H9F3N2O/c14-13(15,16)9-4-3-5-10(8-9)18-12(19)11-6-1-2-7-17-11/h1-8H,(H,18,19)
UniProtKB/SwissProt

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CHEMBL
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Article
PubMed
n/an/an/an/a>5.00E+3n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Activity at human mGluR4 receptor expressed in CHO cells assessed as effect on calcium mobilization


J Med Chem 52: 4115-8 (2009)


Article DOI: 10.1021/jm9005065
BindingDB Entry DOI: 10.7270/Q2RJ4JHT
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGlu4)


(Rattus norvegicus (Rat))
BDBM50293719
PNG
(CHEMBL571453 | N-(3-(trifluoromethyl)phenyl)picoli...)
Show SMILES FC(F)(F)c1cccc(NC(=O)c2ccccn2)c1
Show InChI InChI=1S/C13H9F3N2O/c14-13(15,16)9-4-3-5-10(8-9)18-12(19)11-6-1-2-7-17-11/h1-8H,(H,18,19)
UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
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Article
PubMed
n/an/an/an/a 1.80E+3n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Activity at rat mGluR4 receptor expressed in HEK293 cells assessed as effect on thallium flux


J Med Chem 52: 4115-8 (2009)


Article DOI: 10.1021/jm9005065
BindingDB Entry DOI: 10.7270/Q2RJ4JHT
More data for this
Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM50293719
PNG
(CHEMBL571453 | N-(3-(trifluoromethyl)phenyl)picoli...)
Show SMILES FC(F)(F)c1cccc(NC(=O)c2ccccn2)c1
Show InChI InChI=1S/C13H9F3N2O/c14-13(15,16)9-4-3-5-10(8-9)18-12(19)11-6-1-2-7-17-11/h1-8H,(H,18,19)
KEGG

GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a 1.83E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2DR2SWV
More data for this
Ligand-Target Pair