BDBM50293742 CHEMBL569148::N-(4-cyano-3-(trifluoromethyl)phenyl)picolinamide::cid_44191179

SMILES FC(F)(F)c1cc(NC(=O)c2ccccn2)ccc1C#N

InChI Key InChIKey=YNSZFIUHHIUANF-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293742   

TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt Screening Center For Gpcrs, Ion Channels And Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50293742(CHEMBL569148 | N-(4-cyano-3-(trifluoromethyl)pheny...)
Affinity DataEC50:  1.77E+3nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt Screening Center For Gpcrs, Ion Channels And Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50293742(CHEMBL569148 | N-(4-cyano-3-(trifluoromethyl)pheny...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at human mGluR4 receptor expressed in CHO cells assessed as effect on calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50293742(CHEMBL569148 | N-(4-cyano-3-(trifluoromethyl)pheny...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at rat mGluR4 receptor expressed in HEK293 cells assessed as effect on thallium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed