BDBM50293764 CHEMBL549531::methyl 2-(4-(methylthio)phenylamino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxylate

SMILES COC(=O)c1ccc2n(Cc3ccccc3C(F)(F)F)c(Nc3ccc(SC)cc3)nc2c1

InChI Key InChIKey=CJDPIIDPHBOQDC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293764   

TargetKinesin-like protein KIF11(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293764(CHEMBL549531 | methyl 2-(4-(methylthio)phenylamino...)
Affinity DataIC50:  3.34E+4nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin heavy chain isoform 5A(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293764(CHEMBL549531 | methyl 2-(4-(methylthio)phenylamino...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of nKHCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF3B(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293764(CHEMBL549531 | methyl 2-(4-(methylthio)phenylamino...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Kif3BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed