BindingDB logo
myBDB logout

BDBM50293772 2-(4-methylbenzylamino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxylic acid::CHEMBL549466

SMILES: Cc1ccc(CNc2nc3cc(ccc3n2Cc2ccccc2C(F)(F)F)C(O)=O)cc1

InChI Key: InChIKey=MFZPMGKERBFJRP-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293772   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kinesin-like protein 1


(Homo sapiens)
BDBM50293772
PNG
(2-(4-methylbenzylamino)-1-(2-(trifluoromethyl)benz...)
Show SMILES Cc1ccc(CNc2nc3cc(ccc3n2Cc2ccccc2C(F)(F)F)C(O)=O)cc1
Show InChI InChI=1S/C24H20F3N3O2/c1-15-6-8-16(9-7-15)13-28-23-29-20-12-17(22(31)32)10-11-21(20)30(23)14-18-4-2-3-5-19(18)24(25,26)27/h2-12H,13-14H2,1H3,(H,28,29)(H,31,32)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human kinesin spindle protein by endpoint assay


Bioorg Med Chem Lett 19: 3405-9 (2009)

More data for this
Ligand-Target Pair
Kinesin heavy chain isoform 5A


(Homo sapiens)
BDBM50293772
PNG
(2-(4-methylbenzylamino)-1-(2-(trifluoromethyl)benz...)
Show SMILES Cc1ccc(CNc2nc3cc(ccc3n2Cc2ccccc2C(F)(F)F)C(O)=O)cc1
Show InChI InChI=1S/C24H20F3N3O2/c1-15-6-8-16(9-7-15)13-28-23-29-20-12-17(22(31)32)10-11-21(20)30(23)14-18-4-2-3-5-19(18)24(25,26)27/h2-12H,13-14H2,1H3,(H,28,29)(H,31,32)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Inhibition of nKHC


Bioorg Med Chem Lett 19: 3405-9 (2009)

More data for this
Ligand-Target Pair
Kinesin-like protein KIF3B


(Homo sapiens)
BDBM50293772
PNG
(2-(4-methylbenzylamino)-1-(2-(trifluoromethyl)benz...)
Show SMILES Cc1ccc(CNc2nc3cc(ccc3n2Cc2ccccc2C(F)(F)F)C(O)=O)cc1
Show InChI InChI=1S/C24H20F3N3O2/c1-15-6-8-16(9-7-15)13-28-23-29-20-12-17(22(31)32)10-11-21(20)30(23)14-18-4-2-3-5-19(18)24(25,26)27/h2-12H,13-14H2,1H3,(H,28,29)(H,31,32)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Kif3B


Bioorg Med Chem Lett 19: 3405-9 (2009)

More data for this
Ligand-Target Pair