BDBM50293953 (R)-5-Chloro-3-(4-methoxy-2,5-dimethylphenylamino)-1-[1-(methoxymethyl)propyl]pyrazin-2(1H)-one::CHEMBL552504

SMILES CC[C@H](COC)n1cc(Cl)nc(Nc2cc(C)c(OC)cc2C)c1=O

InChI Key InChIKey=NVLPUZLZJSKPGJ-CYBMUJFWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293953   

TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50293953((R)-5-Chloro-3-(4-methoxy-2,5-dimethylphenylamino)...)
Affinity DataIC50:  0.590nMAssay Description:Displacement of [125I]Tyr-ovine-CRF from CRF1 receptor in rat frontal cortex homogenate by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed