BDBM50293985 (R)-5-Chloro-1-(1-cyclopropylethyl)-3-[6-methoxy-2-(trifluoromethyl)pyridin-3-ylamino]pyrazin-2(1H)-one::(R)-5-chloro-1-(1-cyclopropylethyl)-3-(6-methoxy-2-(trifluoromethyl)pyridin-3-ylamino)pyrazin-2(1H)-one::CHEMBL559764

SMILES COc1ccc(Nc2nc(Cl)cn([C@H](C)C3CC3)c2=O)c(n1)C(F)(F)F

InChI Key InChIKey=FZAUHCBIADRJSU-MRVPVSSYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293985   

TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50293985((R)-5-Chloro-1-(1-cyclopropylethyl)-3-[6-methoxy-2...)
Affinity DataIC50:  1.60nMAssay Description:Displacement of [125I]Tyr-ovine-CRF from CRF1 receptor in rat frontal cortex homogenate by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50293985((R)-5-Chloro-1-(1-cyclopropylethyl)-3-[6-methoxy-2...)
Affinity DataIC50:  1.80nMAssay Description:Displacement of [125I]Tyr-ovine-CRF from CRF1 receptor in rat frontal cortex homogenate by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed