BDBM50294165 (4-(thiophen-2-yl)phenyl)methanamine::1-(4-thiophen-2-ylphenyl)methanamine::CHEMBL539640

SMILES NCc1ccc(cc1)-c1cccs1

InChI Key InChIKey=YKNLMMDEWQZCLJ-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50294165   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Decode Biostructures

Curated by ChEMBL
LigandPNGBDBM50294165((4-(thiophen-2-yl)phenyl)methanamine | 1-(4-thioph...)
Affinity DataIC50:  1.06E+5nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Decode Biostructures

Curated by ChEMBL
LigandPNGBDBM50294165((4-(thiophen-2-yl)phenyl)methanamine | 1-(4-thioph...)
Affinity DataIC50:  9.80E+4nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSChecked by AuthorMore data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Decode Biostructures

Curated by ChEMBL
LigandPNGBDBM50294165((4-(thiophen-2-yl)phenyl)methanamine | 1-(4-thioph...)
Affinity DataIC50:  1.06E+5nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair