BDBM50294203 3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-dimethoxyphenyl)-1-(1-ethylphthalazin-2(1H)-yl)prop-2-en-1-one::CHEMBL560702

SMILES CCC1N(N=Cc2ccccc12)C(=O)\C=C\c1cc(Cc2cnc(N)nc2N)cc(OC)c1OC

InChI Key InChIKey=XIZZHFSPMWESTN-MDZDMXLPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294203   

TargetDihydrofolate reductase(Homo sapiens (Human))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294203(3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-dimet...)
Affinity DataIC50: >2.70E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294203(3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-dimet...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of rat DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed